Ulf Landegren (Uppsala University)

In this episode, Peter sits down with Ulf Landegren, Professor of Molecular Medicine at Uppsala University and a pioneer in DNA-based detection technologies.

Ulf shares the story behind one of his lab’s most important breakthroughs, rolling circle amplification, and how it almost didn’t happen when a student pushed ahead despite his doubts.

He also explores how this technology has evolved into powerful methods for detecting cancer mutations with extraordinary sensitivity, offering new ways to monitor disease and patient outcomes, particularly in leukemia.

Along the way, Ulf reflects on the human side of science—from the role of curiosity and persistence in discovery to lively (and very vocal) scientific debates with his son on family bike rides.

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Creators and Guests

Dr Peter O'Toole
Host
Dr Peter O'Toole
Head of Imaging and Cytometry, York
Ulf Landegren
Guest
Ulf Landegren
Professor at Department of Immunology, Genetics and Pathology, Uppsala University
Ulf Landegren (Uppsala University)